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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Sitting in front of his occupational therapist last week at a Novi rehab facility, 9-year-old Kaden Strek had a choice to make: the green plastic turtle or the blue one.

Kaden-Strek.jpg
 
"Where's the green?" asked his therapist, Sara Wasser.
 
After a slight pause, Kaden reached out and plucked the green turtle out of Wasser's hand. A big smile spread across his face.
 
"Good job!" cheered Wasser.
 
A year ago, Kaden, of St. Clair Shores, couldn't see most colors. Born several months premature, he suffered a severe brain bleed as an infant and was later diagnosed with spastic diplegic cerebral palsy and blindness. As a result, he could only see some shapes, colors and patterns.
 
Now, a year after receiving eight cord blood stem cell infusions in China, Kaden can see not only primary colors but pastels. His language has improved dramatically, and he's saying new words every day and speaking in some sentences, said his mother, Eddie (short for Elizabeth) Strek. Even his walking and balance have improved.

And his family believes stem cells have made all the difference.
 
"This has given him a whole new kind of independence and control over himself that he's never had," Eddie Strek said. "It's so exciting to see."
 
So happy with his improvement over the last year, the Streks are raising money for Kaden to go back to China for another round of stem cell therapy, hopefully next summer. They'll need about $38,000 for treatment and travel costs.

Stem cell therapy is available only for certain conditions in the United States, and cerebral palsy is not among them. The therapy has become a big business overseas, available everywhere from Mexico to Thailand.
 
Treatment programs are offered for a host of conditions, but they're often very expensive, and critics question their efficacy.
 
Beike Biotechnology, the firm that conducted Kaden's stem cell therapy, treats more than 200 international patients a month with stem cell therapy.
 
Researchers such as Larry Goldstein, director of the University of California San Diego's stem cell program, are very wary of overseas programs. They question where the stem cells come from and wonder about possible risks.
 
In a case such as Kaden's, Goldstein said it's hard to tell whether stem cells made a difference or if he improved on his own.
 
"That is what clinical trials are for," he said in an email last week. "Every disease fluctuates in symptoms, and kids with developmental diseases tend to continue developing albeit at different rates. How does one know whether the transplant caused improvement versus intensive physical therapy versus fluctuation versus normal developmental improvements that would have happened anyway?"
 
Eddie Strek disagrees. She said Kaden has received fairly extensive therapy his entire life. He now receives occupational therapy and speech therapy four days a week.
 
"There's just no other explanation" for his progress since the cord blood stem cell infusions, she said.
Eddie said she noticed a change in Kaden's vision within 48 hours after his first infusion in China last summer. She was talking with her husband, Tom, on Skype with Kaden next to her when Kaden wanted to get closer to the screen and was looking intently at his dad.
 
"He can see me!" said Tom.
 
Wasser, an occupational therapist with Children's Hospital of Michigan's Novi rehabilitation facility, said Kaden also is using the left side of his body now, something he didn't really do before stem cells. Kaden is the first patient Wasser has ever worked with who's had a stem cell transplant.
 
"I've been an OT for over 10 years, and this is the first patient I've ever had who has regained vision," Wasser said. "… For him, it's really teaching him to use something that he never had before."
 
That means teaching Kaden basic items such as cat, ball and bike. His mom said he knew what a cat said before, but didn't know what one looked like.
 
Working with Wasser during a recent therapy session, Kaden stared at an augmentative communication device the size of a laptop computer. The screen showed a grid with 15 squares. A bell popped up in one square. Kaden had to track it across the screen and tap it with a small pointer. Eventually, the grid got bigger and the bell got smaller, but he still found the bell.
 
Eddie Strek said it's frustrating that stem cell treatment largely isn't available in the United States, because "so many people could be helped."
 
"These are tangible results," Eddie Strek said. "Anyone that knew him before and sees him now, you can see the results. He's a different kid."


PS from Don Margolis: We featured Kaden last year as the family was preparing to go to China.  You can find that article by putting STREK in the search box above.
Posted: 7/1/2012 2:53:58 PM by Guest Blogger | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
BODY DIES, STEM CELLS GO DORMANT AND SURVIVE FOR 2+ WEEKS
"Scientists around the world are shocked, but they shouldn't be," says Don Margolis
 
Under the direction of Fabrice Chrétien, in collaboration with Shahragim Tajbakhsh, researchers from the Institut Pasteur, the Université de Versailles Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the CNRS have shown for the first time in humans and mice, the capacity of stem cells to adopt a dormant state when their environment becomes hostile, including several days after death. This ability to significantly reduce metabolic activity enables them to preserve their potential for cellular division, even after extended periods post mortem. After isolation, they can then be used to repair damaged organs or tissues. This discovery could lead to new therapeutic avenues for treating numerous diseases. The study is being published in the journal Nature communications.
 
Remarkably, skeletal muscle stem cells can survive for seventeen days in humans and sixteen days in mice, post mortem well beyond the 1-2 days currently thought. This discovery was made by researchers from the Institut Pasteur, the Université de Versailles Saint-Quentin-en-Yvelines, the Paris Public Hospital Network (AP-HP), and the CNRS under the direction of Professor Fabrice Chrétien*, in collaboration with a team led by Professor Shahragim Tajbakhsh**. The scientists were also able to show that these stem cells, once back in culture, retained their capacity to differentiate into perfectly functioning muscle cells.
 
In light of this astonishing result, scientists then sought to characterize these cells to understand how they survive in such adverse conditions. They observed that these cells enter a deeper state of quiescence, drastically lowering their metabolism. This so-called "dormant" state is a result of cellular organization that is stripped to the bare minimum: fewer mitochondria (cellular power plants using oxygen to produce energy in cells) and diminished stores of energy.
“We can compare this to pathological conditions where cells are severely deficient in resources, before regaining a normal cell cycle for regenerating damaged tissues and organs, explains Fabrice Chrétien. When muscle is in the acute phase of a lesion, the distribution of oxygen is highly disrupted. We have even observed that muscle stem cells in anoxia (totally deprived of oxygen) at 4°C have a better survival rate than those regularly exposed to ambient levels of oxygen.”
 
The team of Fabrice Chrétien then wondered if these results were consistent with other cell types. Tests were then done on stem cells taken from bone marrow where blood cells are produced. These cells remained viable for four days in post mortem mice models, and more importantly, they retained their capacity to reconstitute tissue after a bone marrow transplant.
 
This discovery could form the basis of a new source, and more importantly new methods of conservation, for stem cells used to treat a number of pathologies. This is the case for leukemia, for example, which requires a bone marrow transplant to restore a patient's blood and immune cells destroyed by chemotherapy and radiation. By harvesting stem cells from the bone marrow of consenting donors post mortem, doctors could address to a certain extent the shortage of tissues and cells. Although highly promising, this approach in the realm of cellular therapy still requires more testing and validation before it can be used in clinical applications. Nevertheless, it paves the way to investigate the viability of stem cells from all tissues and organs post mortem.
 
Source: Institut Pasteur
 
From Don: "Scientists around the world are shocked, but they shouldn't be, because Repair Stem Cells are created to divide, grow and cure, no matter what the obstacles. There are many many obstacles which can slow or stop that repair, but we are constantly finding ways around them.  Now we know it will be possible in the future to collect stem cells (which are smart enough to go dormant) from a recently deceased body, test them, and use them to help another patient."
Posted: 6/14/2012 5:23:28 PM by Guest Blogger | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Now 13, he is still getting better and better.

Lisa-Biermann.jpg

Lisa Biermann has been dedicated to the improvement of her son’s quality of life. Thus far, she has experienced the miracle of hearing her son speak, as well as many other accomplishments, after she was told he would never be able to perform everyday tasks.


THANX TO PAMELA COTE  
 
Tyler Biermann is a lot like other sixth grade boys. He loves working on his computer, playing video games, riding a bike and watching television. He has a silly sense of humor and is very curious about the world around him.
 
What makes Tyler so very special is the great physical hurdles he has overcome in the past 12 years of his life to be able to do the things that most boys his age seem to do so effortlessly.
When Tyler was born, the umbilical cord was wrapped around his neck, causing a lack of oxygen to his brain that led to Tyler suffering a stroke during delivery. The stroke caused damage to the back of Tyler’s brain. Tyler was diagnosed with cerebral palsy and his mother, Lisa Biermann, was told to expect the worst: a child who would never walk, talk, or have any chance at a normal life.
 
Lisa refused to give up hope. She tried everything she could to help Tyler. Tyler could not walk because his feet would not sit flat on the floor. She tried botox injections every three months, braces, casts and even ankle cord surgery. Nothing worked.
 
Lisa said Tyler could not communicate with her at all. She never knew when he was in pain because he was unable to tell her.
 
Tyler was considered to be blind, with a prescription that was over nine units nearsighted, and his eyes jumped around. Even with glasses, he could not focus his vision, and doctors did not believe he could see, or ever would see.
 
Until he was 8 years old, Lisa would carry Tyler from his classes at Woodland Park Elementary.
 
When Tyler was 8, he had a seizure.  A USA stem cell doctor heard about Tyler and offered to help him with umbilical cord stem cell therapy. Lisa said she thought hard about it, and because she had tried everything else and nothing had worked, she decided to try the stem cell therapy, which she was assured (correctly) that it had no serious side effects.
 
In December 2007, Lisa took Tyler to Mexico for the treatment, which had to be done in Tijuana because stem cells injection was not legal in the United States. 
Nor is it today, five years later.   Nor will it be anytime this decade, according to Don Margolis .  Three months later, they went for a second injection.
 
The stem cells were given to Tyler intravenously for a period of approximately 45 minutes.
 
Lisa said within weeks, she saw monumental changes in Tyler. All the milestones he never reached as a baby, he began reaching.
 
Within three months Tyler could put his feet flat on the floor and could walk independently. At six months post-treatment, he no longer needed the painful braces that gave him bunions.
 
Also within the first three months, Tyler took off his glasses and told Lisa, “no see, Mom.” When Lisa took Tyler to the eye doctor, his vision had improved from nine units nearsighted to 5.5. At six months post-treatment he had improved to four units. He is now at about 1 unit nearsighted and his doctor does not believe that he needs to wear his glasses. Even more impressive is that he can communicate and answer questions posed by the eye doctor.
 
In fact, Tyler, who could not communicate at all before his stem cell treatment, can now say hundreds of words. He can recite the alphabet. Tyler can spell and is even starting to read. He makes the honor roll and has received two spotlight awards from school for his progress.
 
Tyler helps with household chores, can walk up and down the stairs and pour himself something to drink. In December, he decided that he wanted to ride a bike and could not be discouraged from trying. To her great surprise, Lisa said Tyler not only climbed onto his friend’s bike, but he started peddling as well.
 
There have been setbacks along the way. Last April, Lisa took Tyler to the doctor because his blood pressure was very high. The doctor noticed that Tyler had no pulse in his legs and had an MRI performed.
 
The MRI showed that Tyler had a rare birth defect. He only had two heart valves and his aorta was pinched. The MRI also showed that Tyler’s veins and arteries had formed a web around his heart and major organs to supply them with blood. Lisa credits the stem cells for protecting Tyler’s organs.
 
Tyler had surgery to repair his aorta and has recovered well.
 
“He improves every single day,” Lisa said.
 
Lisa hopes to take Tyler for another stem cell treatment this summer. She wants everyone to know that there is hope and shares her experiences and links to others’ stories on her website, www.stemcellhelps.com.
Posted: 5/1/2012 12:11:06 PM by Guest Blogger | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Oakland Raiders linebacker Rolando McClain turned to stem- cell therapy to deal with the aches and pains that come with being a professional football player, the Mobile Press-Register reported Sunday.

Former-Alabama-football-players-get-stem-cell-injections.jpg

 
"It feels a lot better," McClain told the newspaper, adding he has been able to work out with hardly any pain at all."

According to the newspaper, McClain, who missed only one game last season but was hampered by knee pain and an ankle injury, had stem cells taken from his own fat and injected into his knee and leg. McClain credits the procedure for helping him do what he needs to do to prepare for the 2012 season.
 
Jason R. Williams, the radiologist who performed the procedure in Alabama, called the experimental therapy "the future of medicine." However, the newspaper also reported that the FDA has warned consumers about the possible pitfalls of stem-cell treatments.
 
"There is a potential safety risk when you put cells in an area where they are not performing the same biological function as they were when in their original location in the body," said Stephanie Simek, deputy director of the FDA's Office of Cellular, Tissue and Gene Therapies, in a statement.

EDITOR'S NOTE: What the FDA will never tell you is that the "safety risk" of the expensive knee surgeries which the FDA has approved are far far more dangerous to a player's career than stem cell therapy.    ---Don Margolis

Don Margolis

 
The newspaper reported that McClain and fellow University of Alabama product Marquis Maze have sought the treatment. Peyton Manning, who recently joined the Denver Broncos after missing the 2011 season with neck issues, reportedly also had a similar procedure outside of the country.
 
Posted: 4/22/2012 4:13:01 PM by Guest Blogger | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
2012-15: USA Trillionaires Attempting to Match VesCell 2004-06

Baxter Begins Phase III Adult Stem Cell Trial For Chronic Cardiac Condition

(RTTNews.com) - Baxter International Inc. (BAX), valued at over THREE TRILLION DOLLARS, said it has initiated a phase III pivotal clinical trial to evaluate the efficacy and safety of adult autologous CD34+ stem cells to increase exercise capacity in patients with chronic myocardial ischemia.  Should it succeed, and one actuary has placed the odds at very close to 100%, they will have proven what VesCell proved in 2004-06 with capital of less than ONE ONE-MILLIONTH of Baxter's current value!
 
Chronic myocardial ischemia is one of the most severe forms of coronary artery disease, causing significant long-term damage to the heart muscle and disability to the patient.  VesCell (2005-2010) also treated over 200 non-ischemic patients with the same blood-derived stem cells.

Baxter said that the trial will enroll approximately 450 patients across 50 clinical sites in the United States, who will be randomized to one of three arms, namely treatment with their own autologous CD34+ stem cells, treatment with placebo (control), or unblinded standard of care. The primary objective is to evaluate the efficacy of treatment with CD34+ stem cells to improve the functional capacity of patients with chronic myocardial ischemia, as measured by a change in total exercise capacity at 12 months following treatment.
 
Efficacy will be measured by a change in total exercise capacity during the first year following treatment and safety data will be collected for two years.  Exercise capacity (6 minute walk) was the key efficacy factor in the VesCell trial.  Even better, that trial proved 100% safe, and none of the 500 no-hope heart patients treated after that trial was harmed by the patient's own blood-derived stem cells---still in use today and still no one can top them with published scientific data....no one.
 
Baxter noted that the trial is being initiated based on the phase II data, which indicated that injections of patients' own CD34+ stem cells may improve exercise capacity and reduce reports of angina episodes in patients with chronic, severe refractory angina. 
Finally, I have long claimed that no serious heart stem cell treatment which can affect Big Medicine's profits will be approved in any developed country by 2020.  Nothing here has changed that.

Don Margolis, Chairman 
Repair Stem Cell Institute
Co-Founder VesCell/TheraVitae
 
Posted: 2/29/2012 6:35:54 PM by Guest Blogger | with 0 comments


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