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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Instead, Feaster turned to a fledgling Duke University Medical Center program that provides collection kits to mothers and their doctors. When Feaster's daughter, Kadee, arrived last month, the cord blood was collected, packaged and quickly shipped to a blood bank at no cost to Feaster and with minimal commitment of time and expertise from her doctor.

Duke doctor Joanne Kurtzberg wants to replicate Feaster's experience on a large scale.

Kurtzberg hopes that an easier donation process will trigger a surge in donations of blood cells so valuable they've been used to reverse and even cure otherwise fatal disorders. The current cord blood supply can't keep up with the demand for its use in treating leukemia, sickle cell disease and other blood disorders, and the nation's hospital infrastructure isn't set up to tap even a fraction of the potential donors.

It's cheaper this way

Kurtzberg, a pediatrics professor who has pioneered the use of umbilical cord stem cells to treat cancer and genetic disorders in children, believes the kits can spur donations. She's part of a one-year test program financed by the National Marrow Donor Program to develop, distribute and track their effectiveness. Duke is one of three participating blood bank sites, along with the M.D. Anderson Cancer Center in Houston and the Texas Cord Blood Bank in San Antonio.

Kurtzberg directs the Carolinas Cord Blood Bank, a Duke initiative that trains medical personnel and provides resources to collect the valuable blood at seven hospitals across the state, including Rex Healthcare , Durham Regional Hospital and UNC Hospitals. Those are North Carolina's only sites. Fewer than 200 hospitals nationwide do it.

It's costly. Duke pays $750,000 a year to equip each of those sites to collect the blood. But if you don't live near one of those sites, it's tough to donate.
That's where Kurtzberg's new kit comes in. It is a temperature-controlled box sent to expectant mothers at no cost. It includes all required consent forms and all the materials required for the blood collection, along with vials to store samples of the mother's blood, to be checked for infectious disease.

The kits cost $350 to $400 to make and are reusable.

By putting the kits into the hands of expectant mothers, Kurtzberg hopes to spur women to harvest their blood for science. The woman must persuade her doctor to take part; the doctor then takes a 10-minute online training course and agrees to collect the blood during the birth and ship it to a blood bank. The process adds about five minutes to the delivery, Kurtz berg said.

This gift can save lives

Feaster, the mother from Louisiana, learned about donation when her stepsister's two children received cord blood treatments at Duke for neurological disorders.

"Everyone tells you when you have a child that you should bank your cord blood, but it's not always financially possible," she said. "You don't realize how important it is until you know someone who goes through it. I really hope the cord blood from my daughter may help save someone's life. If I had another child I'd do it again."

This blood changes lives. It is rich in stem cells, prized because they can build healthy cells and tissue and repair or replace dead or damaged cells.

Kurtzberg has used cord blood to treat leukemia, metabolic disorders and sickle cell disease, and the parents of sick children flock to her Duke clinic for cord blood transplants.

Some cord blood isn't viable because of infection or other reasons. When collected properly at a medical center, the blood is viable once out of every two to 2 1/2 times, Kurtzberg said. That level of viability may drop with samples collected with the new kits; that's one factor Kurtzberg hopes to study. The program's goal is to collect 500 good samples.

"There's no ethical dilemma because it's otherwise discarded material," Kurtzberg said. "It is literally thrown in the trash, which frustrates a lot of people because it's good stuff..

Read more...

Posted: 7/20/2010 8:23:51 AM by Don Margolis | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
A center in Yerevan that opened recently as part of a larger donor registry to harvest Repair Stem Cells for transplants has registered its first success this week as its collection has proved life-saving for a patient in Europe.

The stem cells of Frederic Safarian, an Iranian-Armenian, matched with those of a non-Armenian woman living in Belgium and suffering from a grave blood-related illness. The transplant was successfully performed on Thursday night in Belgium.

The Stem Cell Harvesting Center in Yerevan is the only such establishment that is available in the territory of the former Soviet Union.

It is part of the Armenian Bone Marrow Donor Registry (ABMDR), which was established in 1999 for recruiting and providing matched unrelated donors for bone marrow or stem cell transplantation to all Armenian and non-Armenian patients who are suffering from leukemia and other blood related illnesses.



About 16,000 donors have been registered with ABMDR so far. A total of 821 matches have been found for 1,276 applications from patients during these years. This week has marked the tenth successful transplant assisted by the charitable organization, but the first stem-cell successfully matched. 

Doctor Mihran Nazaretyan, who works as part of this project, says that such successes not only save human lives, but may also hold out broad prospects for the future of Armenian medicine.

“We want not only to provide donors, but also create a transplant center in Armenia, which, naturally, will cost hundreds of thousands of dollars, but we consider that 70 percent of work to achieve this goal has already been done,” Nazaretyan told ArmeniaNow.

Posted: 6/21/2010 6:54:29 PM by Don Margolis | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
“A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.”
 
WHAT REALLY HAPPENED?
The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.

The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.
 
Dr. Gero Hütter isn’t an AIDS specialist, but he ‘functionally cured’ a patient, who shows no sign of the disease.
“I was very surprised,” said the doctor, Gero Hütter.

The breakthrough appears to be that Dr. Hütter, a soft-spoken hematologist who isn’t an AIDS specialist, deliberately replaced the patient’s bone marrow cells with those from a donor who has a naturally occurring genetic mutation that renders his cells immune to almost all strains of HIV, the virus that causes AIDS.

FANTASTIC! BUT WHILE THIS IS GREAT NEWS, IT IS NOT “NEW” NEWS…
Why does this sound familiar?
  1. The original article that got almost no coverage is from Wall Street Journal – Nov 2008http://online.wsj.com/article/SB122602394113507555.html?mod=googlenews_wsj#articleTabs%3Darticle
  2. This article was then posted here in Feb 2009http://repairstemcell.wordpress.com/2009/02/20/stem-cells-hiv-part-2-a-doctor-a-mutation-and-a-potential-cure-for-aids-wsjcom/
  3. The abstract of the case was posted in the New England Journal of Medicine in Feb 2009 – See abstract below
SO WHY IS IT ONLY NOW GETTING PICKED UP BY THE MEDIA??
Good question….Perhaps because they have been ordered to not publish anything other than embryonic stem cell stories over the past 3 years or so? SCREW THE EMBRYOS, THEY’RE IRRELEVANT!

Some clarifications on the story:
  • There were no embryos involved in this.  Any time you see the words “treated” or “improved” or “recovered” associated with the words “stem cells”, assume it was from adult or repair stem cells until proven otherwise. http://repairstemcell.wordpress.com/stem-cells-for-newbies/
  • In this case, there were 80 compatible blood donors living in Germany and on the 61st sample tested, they found one with the “retrovirus resistant” mutation from both parents.
  • I’ve been told the procedure cost about $150k.
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell TransplantationSUMMARY
 
Infection with the human immunodeficiency virus type 1 (HIV-1)requires the presence of a CD4 receptor and a chemokine receptor,principally chemokine receptor 5 (CCR5). Homozygosity for a32-bp deletion in the CCR5 allele provides resistance againstHIV-1 acquisition. We transplanted stem cells from a donor whowas homozygous for CCR5 delta32 in a patient with acute myeloidleukemia and HIV-1 infection. The patient remained without viralrebound 20 months after transplantation and discontinuationof antiretroviral therapy. This outcome demonstrates the criticalrole CCR5 plays in maintaining HIV-1 infection.
 


Posted: 3/8/2010 4:29:14 PM by Don Margolis | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.

Stem Cell Research Produces Another Miracle of Adult Stem Cells


Here is another miracle story in which stem cell research using Adult Stem Cells played the star role.  Kim Case, a woman from Gaston, Oregon was given little hope to live after being diagnosed with NK T-cell Lymphoma.  In fact, Kim was the first caucasian in the United States to have had this deadly form of Lymphoma.

Chemotherapy Ineffective Against Lymphoma


Kim went through radiation treatments and 3 rounds of chemotherapy.  All were ineffective against the lymphoma. Her only hope was adult stem cells from a matching donor.

Lucky to Find Match for Adult Stem Cell Transplant


Kim was very lucky in this regard.  She found a matching donor within one week.  Normally it takes 6 months to a year to find a donor and many lymphoma patients die waiting for the right match.  Kim's hero was Doug Cokinis a 42 year old male with matching adult stem cells.

From the stem cell article:

After another chemotherapy session, the stem cell transplant took place in October 2004.

It took about a month before Kim re-gained some strength.

"It was a gradual, slow process," she said. "I had to walk three or four times around my room without stopping before being allowed to leave the hospital."

Able to leave the hospital after 52 days, Kim stayed in Seattle to go back in for occasional tests.

"They gave her a list of things she'd have problems with for the rest of her life," Jay said.

So, the short period of time after that was nothing short of remarkable.

She was able to return home in February 2005, cancer free. She regularly had blood draws to make sure the cancer had not returned.

By June 2005, she was able to stop taking medication for side effects from cancer. She hasn't taken any medication since then – something unheard of in cancer patients.

How to Become A Stem Cell Transplant Donor


Kim had something to say to everyone  about being possible donors at the Red Cross--
"It's an easy process," Kim said. "They take blood to test for diseases. Once that's clear, they put you on a list. Once they find a match, they give you shots to take for the cells to reproduce at a faster rate ... most don't know what to an adult stem cell transplant is, it's not like a bone marrow transplant."

Considering all that had happened to her, Kim took no time in answering whether or not she thought her experience was, in fact, a miracle.

"One hundred percent miracle," she said.
Here is another stem cell success story and information on how you can possibly save a life by giving the greatest gift of all- the gift of life.
Posted: 7/10/2009 11:56:41 AM by Don Margolis | with 0 comments


Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Why all the emphasis on Embryonic Stem Cell research and so little written about Adult Stem Cell Research?

Researchers have known about adult stem cells (ASC) for 40 years, embryonics (ESC) for almost as long. For most of that time, bone marrow and ASC have been successfully used to help certain forms of cancer, leukemia and a couple of uncommon diseases. Then, in 1998, two events in the USA shook the ground of the medical world forever, though it wasn’t immediately clear how it would play out.

At the University of Wisconsin, Madison, Dr. Jamie Thomson isolated, for the first time, a line of embryonic stem cells. Meanwhile, at Duke University, Prof. Doris Taylor wrote the seminal paper which let the world know that ASC had helped cure heart disease in rodents. Both doctors thought human benefits would be a very long time away.

Thomson was correct, saying it would take “decades.” Taylor was, in her own words, “a little naïve” for not realizing that the medical community would take off and use her concept virtually immediately! First came a year or two of animal tests, then, in Paris, 2000, doctors gave a dying 70-year-old heart patient bone marrow cells and he lived four years, at which time the doctors ‘fessed up and released his name. In 2001, USA pioneer Warren Sherman, MD (Columbia U, Mt. Sinai NY Hosp) went to Rotterdam and became the first American to implant ASC into a human heart. However, if you can believe it, the same Sherman, calls those that have taken forward what he did eight years ago, “snake oil salesmen.”

In 2002, a very daring clinical trial led by Dr. Hans Dohmann plus six colleagues in Brazil took 21 transplant candidates and gave 14 of them bone marrow cells. The results were so spectacular that the AHA accepted the paper and it was presented in 2003. Five of the seven in the control group opted in to make a total of 19 stem cell transplants. The mortality rate for transplant candidates is about 35% per year. At that rate there would be, of those 19, only 2.2 patients still alive after five years. There were, in fact, 12 alive as of Dec. 31, 2007; more than five years down the road.

In 2003, Dr. Andreas Zeiher of the Goethe Institute in Frankfurt began much larger trials. As of 2007, he has overseen more ASC implants into hearts than anyone, both in and out of clinical trials.

In 2004, Dr. Amit Patel of Pittsburgh completed two of the most successful trials ever, especially when, in Uruguay, he proved, on a group of ischemic heart failure patients, that a bypass plus cells was infinitely better than a bypass only. That same year, TheraVitae, in Israel, developed a new, powerful blood-derived stem cell and dared to treat the sickest patients no clinical trial would consider. Also in 2004, one of the Brazilians, Dr. Perin, came to Texas and used the Brazil results to get the first ASC heart clinical trial approved by the FDA. Over a dozen such approvals were granted in the next 12-18 months.

Meanwhile, around the world, while USA stem cell research remains mired in politics instead of science, ASC advances in virtually every sector of medicine are rocketing forward without any sign of letting up. In 2005, Drs. Vina & Saslavsky in Argentina completed the very first successful diabetes2 stem cell clinical trial in the world: 13 out of 16 successfully cured. Spinal problems and emphysema and renal failure and cirrhosis of the liver treatments will be moving to the forefront in 2008-9. (Yes, but mostly in China and elsewhere, while Americans die with those diseases without a chance of help from their “doctors.”

TheraVitae has published two papers showing that ASC could easily produce the neurons that embryonic fanatics still lie about and claim cannot happen. That opened the way to research brain and nerve and immune system disorders, but America isn’t even trying. China is showing the way for neurological disorders such as Parkinson’s, Spinal Cord Injury, Stroke, Multiple Sclerosis and others, including what is secretly America’s fastest growing disease, Autism . By 2015 we’ll see some trials, and, knowing ASC, they will be successful, but will NOT lead to treatments. Proof? Those above-mentioned USA heart clinical trials are now five years down the road from Dr. Perin’s approval. Not a prayer of helping anyone in the next five years, because the American Medical System will not allow its profits to be disturbed.

Oh, and embryonics---nothing to report. Not one person helped. Not one trial approved (or even applied for). ** But lots of press releases bragging about “discoveries” and promising the moon and even the stars. Jamie Thomson, however, was spot-on when he said “decades.” To try to quiet the politics, he even helped invent a way to get ESC from adult skin, but that won’t work until 2010, if then, and, at best, we’ll still be where we are today, which is: ESC have not been involved in any of the about 2000 world-wide stem cell clinical trials, and won’t be tried in one anytime soon.

**To be historically correct, there was one embryonic trial “approved” in January 2009. Don Margolis is on record as saying that trial is a clinical sham and will not start in “early summer 2009 as publicized.”
Posted: 4/6/2009 1:29:00 PM by Don Margolis | with 0 comments


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