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Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
A center in Yerevan that opened recently as part of a larger donor registry to harvest Repair Stem Cells for transplants has registered its first success this week as its collection has proved life-saving for a patient in Europe.

The stem cells of Frederic Safarian, an Iranian-Armenian, matched with those of a non-Armenian woman living in Belgium and suffering from a grave blood-related illness. The transplant was successfully performed on Thursday night in Belgium.

The Stem Cell Harvesting Center in Yerevan is the only such establishment that is available in the territory of the former Soviet Union.

It is part of the Armenian Bone Marrow Donor Registry (ABMDR), which was established in 1999 for recruiting and providing matched unrelated donors for bone marrow or stem cell transplantation to all Armenian and non-Armenian patients who are suffering from leukemia and other blood related illnesses.

About 16,000 donors have been registered with ABMDR so far. A total of 821 matches have been found for 1,276 applications from patients during these years. This week has marked the tenth successful transplant assisted by the charitable organization, but the first stem-cell successfully matched. 

Doctor Mihran Nazaretyan, who works as part of this project, says that such successes not only save human lives, but may also hold out broad prospects for the future of Armenian medicine.

“We want not only to provide donors, but also create a transplant center in Armenia, which, naturally, will cost hundreds of thousands of dollars, but we consider that 70 percent of work to achieve this goal has already been done,” Nazaretyan told ArmeniaNow.

Posted: 6/21/2010 6:54:29 PM by Don Margolis | with 0 comments

Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
“A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.”
The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.

The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.
Dr. Gero Hütter isn’t an AIDS specialist, but he ‘functionally cured’ a patient, who shows no sign of the disease.
“I was very surprised,” said the doctor, Gero Hütter.

The breakthrough appears to be that Dr. Hütter, a soft-spoken hematologist who isn’t an AIDS specialist, deliberately replaced the patient’s bone marrow cells with those from a donor who has a naturally occurring genetic mutation that renders his cells immune to almost all strains of HIV, the virus that causes AIDS.

Why does this sound familiar?
  1. The original article that got almost no coverage is from Wall Street Journal – Nov 2008http://online.wsj.com/article/SB122602394113507555.html?mod=googlenews_wsj#articleTabs%3Darticle
  2. This article was then posted here in Feb 2009http://repairstemcell.wordpress.com/2009/02/20/stem-cells-hiv-part-2-a-doctor-a-mutation-and-a-potential-cure-for-aids-wsjcom/
  3. The abstract of the case was posted in the New England Journal of Medicine in Feb 2009 – See abstract below
Good question….Perhaps because they have been ordered to not publish anything other than embryonic stem cell stories over the past 3 years or so? SCREW THE EMBRYOS, THEY’RE IRRELEVANT!

Some clarifications on the story:
  • There were no embryos involved in this.  Any time you see the words “treated” or “improved” or “recovered” associated with the words “stem cells”, assume it was from adult or repair stem cells until proven otherwise. http://repairstemcell.wordpress.com/stem-cells-for-newbies/
  • In this case, there were 80 compatible blood donors living in Germany and on the 61st sample tested, they found one with the “retrovirus resistant” mutation from both parents.
  • I’ve been told the procedure cost about $150k.
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell TransplantationSUMMARY
Infection with the human immunodeficiency virus type 1 (HIV-1)requires the presence of a CD4 receptor and a chemokine receptor,principally chemokine receptor 5 (CCR5). Homozygosity for a32-bp deletion in the CCR5 allele provides resistance againstHIV-1 acquisition. We transplanted stem cells from a donor whowas homozygous for CCR5 delta32 in a patient with acute myeloidleukemia and HIV-1 infection. The patient remained without viralrebound 20 months after transplantation and discontinuationof antiretroviral therapy. This outcome demonstrates the criticalrole CCR5 plays in maintaining HIV-1 infection.

Posted: 3/8/2010 4:29:14 PM by Don Margolis | with 0 comments

Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.

Stem Cell Research Produces Another Miracle of Adult Stem Cells

Here is another miracle story in which stem cell research using Adult Stem Cells played the star role.  Kim Case, a woman from Gaston, Oregon was given little hope to live after being diagnosed with NK T-cell Lymphoma.  In fact, Kim was the first caucasian in the United States to have had this deadly form of Lymphoma.

Chemotherapy Ineffective Against Lymphoma

Kim went through radiation treatments and 3 rounds of chemotherapy.  All were ineffective against the lymphoma. Her only hope was adult stem cells from a matching donor.

Lucky to Find Match for Adult Stem Cell Transplant

Kim was very lucky in this regard.  She found a matching donor within one week.  Normally it takes 6 months to a year to find a donor and many lymphoma patients die waiting for the right match.  Kim's hero was Doug Cokinis a 42 year old male with matching adult stem cells.

From the stem cell article:

After another chemotherapy session, the stem cell transplant took place in October 2004.

It took about a month before Kim re-gained some strength.

"It was a gradual, slow process," she said. "I had to walk three or four times around my room without stopping before being allowed to leave the hospital."

Able to leave the hospital after 52 days, Kim stayed in Seattle to go back in for occasional tests.

"They gave her a list of things she'd have problems with for the rest of her life," Jay said.

So, the short period of time after that was nothing short of remarkable.

She was able to return home in February 2005, cancer free. She regularly had blood draws to make sure the cancer had not returned.

By June 2005, she was able to stop taking medication for side effects from cancer. She hasn't taken any medication since then – something unheard of in cancer patients.

How to Become A Stem Cell Transplant Donor

Kim had something to say to everyone  about being possible donors at the Red Cross--
"It's an easy process," Kim said. "They take blood to test for diseases. Once that's clear, they put you on a list. Once they find a match, they give you shots to take for the cells to reproduce at a faster rate ... most don't know what to an adult stem cell transplant is, it's not like a bone marrow transplant."

Considering all that had happened to her, Kim took no time in answering whether or not she thought her experience was, in fact, a miracle.

"One hundred percent miracle," she said.
Here is another stem cell success story and information on how you can possibly save a life by giving the greatest gift of all- the gift of life.
Posted: 7/10/2009 11:56:41 AM by Don Margolis | with 0 comments

Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.
Why all the emphasis on Embryonic Stem Cell research and so little written about Adult Stem Cell Research?

Researchers have known about adult stem cells (ASC) for 40 years, embryonics (ESC) for almost as long. For most of that time, bone marrow and ASC have been successfully used to help certain forms of cancer, leukemia and a couple of uncommon diseases. Then, in 1998, two events in the USA shook the ground of the medical world forever, though it wasn’t immediately clear how it would play out.

At the University of Wisconsin, Madison, Dr. Jamie Thomson isolated, for the first time, a line of embryonic stem cells. Meanwhile, at Duke University, Prof. Doris Taylor wrote the seminal paper which let the world know that ASC had helped cure heart disease in rodents. Both doctors thought human benefits would be a very long time away.

Thomson was correct, saying it would take “decades.” Taylor was, in her own words, “a little naïve” for not realizing that the medical community would take off and use her concept virtually immediately! First came a year or two of animal tests, then, in Paris, 2000, doctors gave a dying 70-year-old heart patient bone marrow cells and he lived four years, at which time the doctors ‘fessed up and released his name. In 2001, USA pioneer Warren Sherman, MD (Columbia U, Mt. Sinai NY Hosp) went to Rotterdam and became the first American to implant ASC into a human heart. However, if you can believe it, the same Sherman, calls those that have taken forward what he did eight years ago, “snake oil salesmen.”

In 2002, a very daring clinical trial led by Dr. Hans Dohmann plus six colleagues in Brazil took 21 transplant candidates and gave 14 of them bone marrow cells. The results were so spectacular that the AHA accepted the paper and it was presented in 2003. Five of the seven in the control group opted in to make a total of 19 stem cell transplants. The mortality rate for transplant candidates is about 35% per year. At that rate there would be, of those 19, only 2.2 patients still alive after five years. There were, in fact, 12 alive as of Dec. 31, 2007; more than five years down the road.

In 2003, Dr. Andreas Zeiher of the Goethe Institute in Frankfurt began much larger trials. As of 2007, he has overseen more ASC implants into hearts than anyone, both in and out of clinical trials.

In 2004, Dr. Amit Patel of Pittsburgh completed two of the most successful trials ever, especially when, in Uruguay, he proved, on a group of ischemic heart failure patients, that a bypass plus cells was infinitely better than a bypass only. That same year, TheraVitae, in Israel, developed a new, powerful blood-derived stem cell and dared to treat the sickest patients no clinical trial would consider. Also in 2004, one of the Brazilians, Dr. Perin, came to Texas and used the Brazil results to get the first ASC heart clinical trial approved by the FDA. Over a dozen such approvals were granted in the next 12-18 months.

Meanwhile, around the world, while USA stem cell research remains mired in politics instead of science, ASC advances in virtually every sector of medicine are rocketing forward without any sign of letting up. In 2005, Drs. Vina & Saslavsky in Argentina completed the very first successful diabetes2 stem cell clinical trial in the world: 13 out of 16 successfully cured. Spinal problems and emphysema and renal failure and cirrhosis of the liver treatments will be moving to the forefront in 2008-9. (Yes, but mostly in China and elsewhere, while Americans die with those diseases without a chance of help from their “doctors.”

TheraVitae has published two papers showing that ASC could easily produce the neurons that embryonic fanatics still lie about and claim cannot happen. That opened the way to research brain and nerve and immune system disorders, but America isn’t even trying. China is showing the way for neurological disorders such as Parkinson’s, Spinal Cord Injury, Stroke, Multiple Sclerosis and others, including what is secretly America’s fastest growing disease, Autism . By 2015 we’ll see some trials, and, knowing ASC, they will be successful, but will NOT lead to treatments. Proof? Those above-mentioned USA heart clinical trials are now five years down the road from Dr. Perin’s approval. Not a prayer of helping anyone in the next five years, because the American Medical System will not allow its profits to be disturbed.

Oh, and embryonics---nothing to report. Not one person helped. Not one trial approved (or even applied for). ** But lots of press releases bragging about “discoveries” and promising the moon and even the stars. Jamie Thomson, however, was spot-on when he said “decades.” To try to quiet the politics, he even helped invent a way to get ESC from adult skin, but that won’t work until 2010, if then, and, at best, we’ll still be where we are today, which is: ESC have not been involved in any of the about 2000 world-wide stem cell clinical trials, and won’t be tried in one anytime soon.

**To be historically correct, there was one embryonic trial “approved” in January 2009. Don Margolis is on record as saying that trial is a clinical sham and will not start in “early summer 2009 as publicized.”
Posted: 4/6/2009 1:29:00 PM by Don Margolis | with 0 comments

Are you or a loved one interested in receiving stem cell treatment? For free information, please fill out our treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box and the MEDICAL CONDITION in the message.

Stem Cell Research and Treatment for Congestive Heart Failure

Stem Cell research has produced another miracle in the form of Adult Stem Cells. Mike Rumble, a dilated cardiomyopathy and congestive heart failure patient from Florida  is now reporting his ejection fraction has tripled after receiving stem cell therapy in the form of his own Adult Stem Cells.

I first featured Mike here in December 2008, Mike was treated by Vescell adult stem cells for his dilated cardiomyopathy and congestive heart failure in Bangkok, Thailand in May 2008. Now, 10 months later, Mike is doing much better.

Before Vescell stem cells

  • Ejection Fraction at 10%

After Stem Cell Treatment using Adult Stem Cells

  • Ejection Fraction at 30%

Second Time Adult Stem Cell Research Has Saved Him

This was Mike's second close brush with death.  The first came in 1989 when he was in the hospital for six months for AML Leukemia which he survived due to Adult Stem Cell research in the form of a bone marrow transplant.

More Energy Due to the Stem Cells

With the renewed energy and heart function given to him by the stem cells, Mike has been able to go back to work at his job as a professional chaplain where he counsels dying patients in hospitals and hospices.  Mike has also been able to open up his own counseling business.

Still More Hurdles After Stem Cell Therapy

However,  Mike isn't out of the woods yet.   Unfortunately, Adult Stem Cell research can't help with valve repair.  Therefore, Mike is trying to get into a clinical trial in which they use a special clip  to correct severe mitral valve regurgitation.  Mike hopes his condition will improve even more if he is able to do it.

Thanks to Vescell blog for the story
Mike also has his own personal stem cell therapy blog
Posted: 3/3/2009 10:49:55 AM by Don Margolis | with 0 comments

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