Are you or a loved one interested in receiving stem cell treatment? For free treatment information, please fill out our
treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box.
Are you or a loved one interested in receiving stem cell treatment? For free treatment information, please fill out our
treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box.
Are you or a loved one interested in receiving stem cell treatment? For free treatment information, please fill out our
treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box.
“A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.”
WHAT REALLY HAPPENED?
The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.
The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.
Dr. Gero Hütter isn’t an AIDS specialist, but he ‘functionally cured’ a patient, who shows no sign of the disease.
“I was very surprised,” said the doctor, Gero Hütter.
The breakthrough appears to be that Dr. Hütter, a soft-spoken hematologist who isn’t an AIDS specialist, deliberately replaced the patient’s bone marrow cells with those from a donor who has a naturally occurring genetic mutation that renders his cells immune to almost all strains of HIV, the virus that causes AIDS.
FANTASTIC! BUT WHILE THIS IS GREAT NEWS, IT IS NOT “NEW” NEWS…
Why does this sound familiar?
- The original article that got almost no coverage is from Wall Street Journal – Nov 2008 – http://online.wsj.com/article/SB122602394113507555.html?mod=googlenews_wsj#articleTabs%3Darticle
- This article was then posted here in Feb 2009 – http://repairstemcell.wordpress.com/2009/02/20/stem-cells-hiv-part-2-a-doctor-a-mutation-and-a-potential-cure-for-aids-wsjcom/
- The abstract of the case was posted in the New England Journal of Medicine in Feb 2009 – See abstract below
SO WHY IS IT ONLY NOW GETTING PICKED UP BY THE MEDIA??
Some clarifications on the story:
- In this case, there were 80 compatible blood donors living in Germany and on the 61st sample tested, they found one with the “retrovirus resistant” mutation from both parents.
- I’ve been told the procedure cost about $150k.
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation - SUMMARY
Infection with the human immunodeficiency virus type 1 (HIV-1)requires the presence of a CD4 receptor and a chemokine receptor,principally chemokine receptor 5 (CCR5). Homozygosity for a32-bp deletion in the CCR5 allele provides resistance againstHIV-1 acquisition. We transplanted stem cells from a donor whowas homozygous for CCR5 delta32 in a patient with acute myeloidleukemia and HIV-1 infection. The patient remained without viralrebound 20 months after transplantation and discontinuationof antiretroviral therapy. This outcome demonstrates the criticalrole CCR5 plays in maintaining HIV-1 infection.
Are you or a loved one interested in receiving stem cell treatment? For free treatment information, please fill out our
treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box.
EXCELLENT RESPONSE IN 5 YEAR-OLD GIRL WITH CEREBRAL PALSY/BRAIN DAMAGE AT BIRTH
March 6, 2010
The quality and quantity of a doctor's Repair Stem Cell treatment created a unique response in a 5 year-old girl with brain damage, paralyzed since birth [her SC treatment was performed at a stem cell clinic very recently].
Three days after infusion of 40 million [umbilical and placenta] stem cells prepared by the doctor's lab, the parents of the child called stating that their little girl started crawling into cabinets, then walking into cabinets & closets, pulling at objects and wandering about in their home.
This is the first time [she's ever done any of this] since birth 5 years ago. This is so far the best results that this doctor and another treating stem cell doctor has seen in the dozens of children treated. [The huge improvements are attribute to] Great stem cell culture and expansion in quantity to 40 million. All of the treating doctor's stem cells are fresh, unfrozen stem cells expanded in an incubator.
Not only is there no freezing, there is no DMSO used (Dimethyl sulfoxide - a chemical added to the Repair Stem Cells to prevent damage during freezing). No chemicals at all.
Are you or a loved one interested in receiving stem cell treatment? For free treatment information, please fill out our
treatment form or email me don@repairstemcells.org and just put TREATMENT in the subject box.
Stem Cells Saved Her Life From CIPD
Stem cell research using a patient's own stem cells has saved a woman from chronic inflammatory demyelinating polyneuropathy (CIPD). Jennifer Osman received a stem cell transplant in 2005 that has probably saved her life.
CIPD is an inflammation of the nerves that leads to a loss of movement or sensation. Jennifer had given up hope when by chance, she was watching TV and saw a report about a stem cell research program for multiple sclerosis at
Northwestern University with Dr. Richard Burt. The next day, Jennifer called Northwestern and learned they were starting a trial for chronic inflammatory demyelinating polyneuropathy, a disease similar to MS.
Below, see Jennifer and her loving husband, Rick.
From the
stem cell news story:
The next day, she called Northwestern and learned hospital officials had been searching for qualified CIDP patients to enroll in a similar program.
"This was my first hope for life."
Her request for the experimental research treatment was initially turned down by her insurance company, but several letters from doctors and family members, as well as a financial breakdown of how the experimental program, though pricey, would still be less costly than a lifetime of the approved plasma treatments that weren't working, convinced her HMO to sign off on it.
"I was approved on my birthday," she said.
Though the hospital had been successful in treating MS patients this way, hers was the first such treatment for CIDP. No one knew what to expect.
HOW IT WORKS
In February 2005, the process of collecting stem cells began for Jennifer Osman's experimental treatment. Once doctors had gathered and frozen between 1 million and 2 million stem cells, they would knock out Jennifer's immune system and restart everything with the harvested and treated cells.
The harvesting complete, Jennifer was then blasted with high doses of chemotherapy for five days until her immune system was virtually wiped out.
Once Jennifer's blood count had been zapped, the treated stem cells were injected back into her body. It would take weeks for them to work their way into her bone marrow, creating more healthy cells and, in theory, overtaking the Chronic Inflammatory Demyelinating Polyneuropathy that was attacking her peripheral nervous system.
The Power Of Adult Stem Cells- Americans Need It Now
Jennifer is now perfectly fine thanks to the power of adult stem cells. While so many marvel at the "potential" of embryonic stem cells which are great at creating tumors, adult stem cells are now helping patients improve their quality of life. Jennifer was lucky enough to qualify for a clinical trial, thousands of other Americans are not as lucky as the FDA has made it all, but impossible to get this stem cell treatment